The definition and classification of psychopathology has critical implications for research, practice, and policy. With the next edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) slated for release in 2013, there is a window of opportunity to revisit strengths and limitations of the current system and to consider ways in which it may be improved. This course will consider the challenges inherent in classifying psychopathology, review historical and contemporary approaches to psychiatric classification, and explore the many controversies that are being hotly debated in the run-up to DSM-5. We will critically examine proposed revisions to disorders and criteria as well as proposed alternatives to the DSM system. Particular attention will be paid to empirical methods of evaluating and improving classification systems. Radically different approaches already being considered for future systems will also be discussed.